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Contact |
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Fischer Fabian |
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Title |
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Biofilm vivacity and destruction on antimicrobial nanosurfaces assayed within a microbial fuel cell |
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Author(s) |
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Marc Sugnaux, Fabian Fischer |
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References |
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Nanomedicine: Nanotechnology, Biology, and Medicine 12 (2016) 1471-1477 |
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Url |
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http://dx.doi.org/10.1016/j.nano.2016.03.008 |
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Abstract |
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A novel method was developed to assay the antimicrobial capacity of nanostructured surfaces for medical implants in a bicathodic microbial fuel cell. Nano-structured gold surfaces with protruding nanopillars and nanorings were investigated. Escherichia coli K12 were used as a model microbe to record electronic effects caused by the interaction with nanosurfaces. The nanostructured gold surfaces enabled power density maxima
up to 1910 mW/m2, indicating fair vivacity, while flat surfaces on the nanoscale provided almost no power 0.35 mW/m2. The biofilmpresence on antimicrobial nanosurfaces was confirmed by the addition of ampicillin and its bactericidal effect resulted in oscillating and declining potentiometric signals. Current density experiments showed that biofilms on antimicrobial nanostructured electrodes caused low currents, indicating that E.coli biofilm remained functional before destruction. The bicathodic microbial fuel cell sensor is a novel tool for evaluating antimicrobial effects caused by nanosurfaces and antibiotics. |
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