return

Biofilm vivacity and destruction on antimicrobial nanosurfaces assayed within a microbial fuel cell


 
 
Contact   Fischer Fabian
 
Title   Biofilm vivacity and destruction on antimicrobial nanosurfaces assayed within a microbial fuel cell
 
Author(s)   Marc Sugnaux, Fabian Fischer
 
References   Nanomedicine: Nanotechnology, Biology, and Medicine 12 (2016) 1471-1477
 
Url   http://dx.doi.org/10.1016/j.nano.2016.03.008
 
Abstract   A novel method was developed to assay the antimicrobial capacity of nanostructured surfaces for medical implants in a bicathodic microbial fuel cell. Nano-structured gold surfaces with protruding nanopillars and nanorings were investigated. Escherichia coli K12 were used as a model microbe to record electronic effects caused by the interaction with nanosurfaces. The nanostructured gold surfaces enabled power density maxima up to 1910 mW/m2, indicating fair vivacity, while flat surfaces on the nanoscale provided almost no power 0.35 mW/m2. The biofilmpresence on antimicrobial nanosurfaces was confirmed by the addition of ampicillin and its bactericidal effect resulted in oscillating and declining potentiometric signals. Current density experiments showed that biofilms on antimicrobial nanostructured electrodes caused low currents, indicating that E.coli biofilm remained functional before destruction. The bicathodic microbial fuel cell sensor is a novel tool for evaluating antimicrobial effects caused by nanosurfaces and antibiotics.
 
 
 
 
HES-SO Valais-Wallis • Route du Rawyl 47 • CP • 1950 Sion 2
+41 27 606 85 11 • info@hevs.ch • www.hevs.ch